Información adicional

• Num_publicacion 74(11)
• Resumen_ingles
  Introduction: Since 1986 has been introduced in our country partial splenectomy, which prevent the recurrence of splenic sequestration crisis and possible reduce the number of overhelming septicemia.
  Objective: Compare clinical and laboratory aspects in patients with total and partial splenectomy.
  Patients and methods: All patients with sickle cell disease were studied, followed at the Instituto de Hematología e Inmunología, who have had a splenectomy in childhood.
  Results: 39 patients were included in each method of splenectomy, where a predominance of males (60.3%) and sickle cell anemia (69.2%). Splenectomy age was lower in the partial, 4.7 years than in total splenectomy, 6.7 years (0.009). Follow-up time was 12.5 years. Total splenectomy group had greater increase in hemoglobin, leucocytes and platelets (p= 0.039), elevated LDH levels (p= 0.015), plasma hemoglobin (p= 0.001) and tricuspid regurgitation velocity (p= 0.038). Vaso-occlusive painful crises was more frequent after total splenectomy (75.8 ± 14.3 vs. 39.8 ± 10.1; p <0.001), as leg ulcer (p= 0.04). Hepatic crisis (p <0.07) and mortality were higher in individuals with complete splenectomy (p= 0.305) but withouth significative statistics.
  Conclusions: Partial splenectomy has fewer long-term complications that total.
   
• Palabras_clave_ingles Partial and total splenectomy Sickle cell disease
• Todos_autores S.A. Machín García, A. Martínez Paneque, A. Gutiérrez Díaz, E. Svarch, A. Menéndez Veitía, M. Gil Agramonte, J. Serrano Mirabal, L. López Martí
• autores listados S.A. Machín García, A. Martínez Paneque, A. Gutiérrez Díaz, E. Svarch, A. Menéndez Veitía, M. Gil Agramonte, J. Serrano Mirabal, L. López Martí
• Correspondecia
  S.A. Machín García. Instituto de Hematología e Inmunología. Calzada de Aldabó y Calle E. Alta Habana. Boyeros (La Habana, Cuba). 10800. Apartado 870.
  Correo electrónico: smachin@hemato.sld.cu
• Titulo_ingles Clinical and hematological evaluation of patients with splenectomized drepanocytosis at the Hematology and Immunology Institute of Cuba: 30 years of experience
• Centros_trabajo Instituto de Hematología e Inmunología. Boyeros (La Habana, Cuba)
• Publicado en Acta Pediatr Esp. 2016; 74(11): e233-e238
• copyright ©2016 Ediciones Mayo, S.A.
• Fecha recepcion 29/03/16
• Fecha aceptacion 27/04/16
• Tipo de Artículo Clínico (Microdatos) Case Reports