Información adicional

• Num_publicacion 75(7-8)
• Resumen_ingles
  Introduction: Changes in diet and obesity are responsible for the emerging nonalcoholic hepatic steatosis (NASH) in children, which may progress to inflammation with fibrosis.
  Objectives: To determine the prevalence of NASH in obese children by ultrasound and to assess the clinical and laboratory data and risk factors.
  Methodology: A pilot study in a selected group of 20 pediatric patients with obesity (BMI + 2.5 DS); prospective registry and descriptive analysis of clinical data questionnaire nutritional habits and lifestyle, physical examination with anthropometric variables, analytical study and ultrasound diagnosis of hepatic steatosis.
  Results: 12 men and 8 women, mean age 12.5 years (range: 6.5 to 16), 100% with a family history of obesity and metabolic disorders, 90% carbohydrate or lipid metabolism disorders (35% LDL, triglycerides 30%); sonographic diagnosis of steatosis in 20%, two of them with hypertransaminasemia (AST 65-35 U/L, ALT 42-100 U/L); 65% had eated between meals, pastries and other sweets (4-5 days a week), and there was predominantly sedentary activity (8.3 h/week) compared to physical exercise (4.2 h/week). 
  Conclusions: The high BMI, dyslipidemia and insulin resistance are risk factors associated with NASH. early intervention can prevent its onset and progression. ultrasonography is safe and it should be considered as a method of early diagnosis in obese children.
   
• Palabras_clave_ingles Fatty liver Ultrasonography Obesity Children
• Todos_autores E. Vaquero Sosa¹, C. Aranda Cazón¹, A. Bodas Pinedo¹, D. Llanos Pérez², D. López de Lara¹, O. Pérez Rodríguez¹
• autores listados E. Vaquero Sosa, C. Aranda Cazón, A. Bodas Pinedo, D. Llanos Pérez, D. López de Lara, O. Pérez Rodríguez
• Correspondecia
  E. Vaquero Sosa. Servicio de Pediatría. Instituto del Niño y del Adolescente. Prof. Martín Lagos, s/n. 28040 Madrid.
  Correo electrónico: estvaqsos@yahoo.es
• Titulo_ingles Nonalcoholic fatty liver disease: prevalence and risk factors in obese children
• Centros_trabajo ¹Servicio de Pediatría. ²Servicio de Radiodiagnóstico. Instituto del Niño y del Adolescente. Hospital Clínico «San Carlos». Madrid
• Publicado en Acta Pediatr Esp. 2017; 75(7-8): e113-e116
• copyright ©2017 Ediciones Mayo, S.A.
• Fecha recepcion 27/06/16
• Fecha aceptacion 28/09/16
• Tipo de Artículo Clínico (Microdatos) Observational Study