Información adicional

• Num_publicacion 67(9)
• Resumen_ingles

  Obesity is one of the main public health problems due to its fast prevalence increase and co-morbidities with several diseases, as the metabolic syndrome, diabetes and cardiovascular diseases. Social changes associated to high intake of energy-dense food and low physical activities have created an obesogenic environment worldwide. In this context, the identification of new factors involved in the regulation of the energy balance has mainly the aim of developing more efficient intervention strategies.

  The intestinal microbiota is considered a new factor involved in the body weight regulation and in diseases associated with obesity through its influence in the metabolic and immunologic functions of the host. The intestinal microbiota and some probiotics also regulate the subject's immunological functions, protecting from infections and chronic inflammation processes. Instead, disorders in the intestinal ecosystem (dysbiosis) and endotoxemia might be inflammatory factors responsible for developing insulin resistance and body weight gain. Based on the relations between the intestinal microbiota, the metabolism and immunity, the use of dietary strategies to modulate the microbiota, based on probiotics and prebiotics, is likely to contribute to the control of the metabolic disorders more efficiently.

• Palabras_clave_ingles Intestinal microbiota probiotics prebiotics obesity metabolic disorders diabetes immunity chronic inflammation
• Todos_autores Y. Sanz, A. Santacruz, J. Dalmau¹
• autores listados Y. Sanz, A. Santacruz, J. Dalmau
• Correspondecia
  Y. Sanz. Ecofisiología Microbiana y Nutrición. Instituto de Agroquímica y Tecnología de Alimentos (IATA). Consejo Superior de Investigaciones Científicas (CSIC). Apartado 73. 46100 Valencia.
  Correo electrónico: yolsanz@iata.csic.es
• Titulo_ingles Influence of the intestinal microbiota on obesity and on metabolic disorders
• Centros_trabajo Ecofisiología Microbiana y Nutrición. Instituto de Agroquímica y Tecnología de Alimentos (IATA). Consejo Superior de Investigaciones Científicas (CSIC). Valencia. ¹Unidad de Nutrición y Metabolopatías. Hospital Infantil «La Fe». Valencia
• Publicado en Acta Pediatr Esp. 2009; 67(9): 437-442
• copyright ©2009 Ediciones Mayo, S.A.
• Fecha recepcion 10/05/09
• Fecha aceptacion 25/05/09